Spontaneous One-Lung Ventilation Increases the Lung Inflammatory Response: An Experimental Pilot Study
نویسندگان
چکیده
منابع مشابه
One-lung ventilation induces hyperperfusion and alveolar damage in the ventilated lung: an experimental study.
BACKGROUND One-lung ventilation (OLV) increases mechanical stress in the lung and affects ventilation and perfusion (V, Q). There are no data on the effects of OLV on postoperative V/Q matching. Thus, this controlled study evaluates the influence of OLV on V/Q distribution in a pig model using a gamma camera technique [single-photon emission computed tomography (SPECT)] and relates these findin...
متن کاملIndependent Lung Ventilation and One Lung Ventilation
The application of the independent lung ventilation (ILV) in adults has been described by Carlon and co-workers in 1978 and subsequently by other investigators. In 1983 Hedenstierna and coworkers using a bilumen tube suitable for prolonged intubation, and two Servo Ventilator 900 B (Siemens) adapted for synchronization, treated a wide range of clinical conditions. Following this experience, the...
متن کاملEffects of propofol and desflurane anaesthesia on the alveolar inflammatory response to one-lung ventilation.
BACKGROUND One-lung ventilation (OLV) induces a pro-inflammatory response including cytokine release and leucocyte recruitment in the ventilated lung. Whether volatile or i.v. anaesthetics differentially modulate the alveolar inflammatory response to OLV is unclear. METHODS Thirty patients, ASA II or III, undergoing open thoracic surgery were randomized to receive either propofol 4 mg kg(-1) ...
متن کاملAnesthetic-induced improvement of the inflammatory response to one-lung ventilation.
BACKGROUND Although one-lung ventilation (OLV) has become an established procedure during thoracic surgery, sparse data exist about inflammatory alterations in the deflated, reventilated lung. The aim of this study was to prospectively investigate the effect of OLV on the pulmonary inflammatory response and to assess possible immunomodulatory effects of the anesthetics propofol and sevoflurane....
متن کاملSpontaneous breathing during high-frequency oscillatory ventilation improves regional lung characteristics in experimental lung injury.
BACKGROUND Maintenance of spontaneous breathing is advocated in mechanical ventilation. This study evaluates the effect of spontaneous breathing on regional lung characteristics during high-frequency oscillatory (HFO) ventilation in an animal model of mild lung injury. METHODS Lung injury was induced by lavage with normal saline in eight pigs (weight range 47-64 kg). HFO ventilation was appli...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Anesthesia & Clinical Research
سال: 2014
ISSN: 2155-6148
DOI: 10.4172/2155-6148.1000428